Hepatic abnormalities in patients with chronic granulomatous disease

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Hepatic abnormalities in patients with chronic granulomatous disease.

UNLABELLED Chronic granulomatous disease (CGD) is a rare congenital disorder characterized by repeated bacterial and fungal infections. Aside from a high incidence of liver abscess, little is known about hepatic involvement in CGD. The aim of this study was to describe the spectrum of liver abnormalities seen in CGD. The charts of 194 patients with CGD followed at the NIH were reviewed, with a ...

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Chronic granulomatous disease with recurrent hepatic abscesses in an adult.

Chronic granulomatous disease CGD is a condition of inability to deal with bacterial and fungal infections, due to defective respiratory burst in neutrophils leading to recurrent cutaneous and visceral infections. Usually a disease of childhood, but patients nowadays survive to adulthood, and diagnosis might be difficult if not considered. We describe a 20-year-old female with previously undiag...

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CT and MRI of hepatic abscess in patients with chronic granulomatous disease.

OBJECTIVE We describe the spectrum of radiologic appearances of hepatic abscesses in patients with chronic granulomatous disease (CGD), a hereditary immunodeficiency presenting in childhood that occurs at a rate of 1 in 200,000-250,000 live births and predisposes patients to infection with catalase-positive organisms. CONCLUSION Hepatic abscesses in patients with CGD show an atypical radiolog...

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gastrointestinal manifestations of patients with chronic granulomatous disease

chronic granulomatous disease (cgd) represents a group of inherited disorders of phagocytic system, manifesting recurrent infections at different sites. the present study was accomplished in order to determine the gastrointestinal manifestations of cgd patients. fifty-seven patients (38 males and 19 females) with cgd, who had been referred to three immunodeficiency referral centers in iran, wer...

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Pulmonary manifestations in adult patients with chronic granulomatous disease.

Chronic granulomatous disease (CGD) is a primary immunodeficiency caused by failure of superoxide production in phagocytic cells. The disease is characterised by recurrent infections and inflammatory events, frequently affecting the lungs. Improvement of life expectancy now allows most patients to reach adulthood. We aimed to describe the pattern of pulmonary manifestations occurring during adu...

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ژورنال

عنوان ژورنال: Hepatology

سال: 2007

ISSN: 0270-9139,1527-3350

DOI: 10.1002/hep.21524